CD360 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-473-0.2mg | 0.2mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
IL21R, CD360, NILR
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.
Background References:
- Hamming O.J., et al., 2012, J. Biol. Chem. 287:9454-9460.
- Kotlarz D., et al., 2013, J. Exp. Med. 210:433-443.
Biological Activity:
Immobilized Biotinylated Human IL-21, Fc Tag at 2ug/mL (100uL/well) can bind Human IL-21 R, His Tag with a linear range of 2-8 ng/mL.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
50615
NCBI Official Name:
interleukin 21 receptor
NCBI Official Symbol:
IL21R
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
25.8 kDa
Protein Accession #:
AAH04348
Purity:
>92% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9HBE5