SRBC Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-098-0.05mg | 0.05mg | £765.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
CD2, SRBC, LFA-2, T11
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5 and SRBC, is a single-pass type I membrane protein found on the surface of T cells and natural killer (NK) cells. CD2 is a member of the immunoglobulin superfamily. CD2 / SRBC contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD2 / SRBC interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3 / CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections.
Background References:
- Wilkins A., et al., 2003, Curr Protein Pept Sci 4 (5): 367?73.
- Yang J., et al., 2001, Curr Protein Pept Sci 2 (1): 1?17.
- Bodian D.L., et al., 1994, Structure 2:755-766.
Biological Activity:
Immobilized Human CD58, Fc Tag at 5 ug/mL (100 uL/well) can bind Human CD2, His Tag with a linear range of 0.02-0.313 ug/mL.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
914
NCBI Official Name:
CD2 molecule
NCBI Official Symbol:
CD2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
22.7 kDa
Protein Accession #:
AAH33583
Purity:
>98% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P06729