CEACAM 8 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-181-0.1mg | 0.1mg | £686.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
CEACAM8, CD66b, CD67, CGM6, NCA-95
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) is also known as CD66b (Cluster of Differentiation 66b), CD66b, CD67, CGM6, NCA-95, and is one of seven human CEACAM family members within the immunoglobulin superfamily. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM8 is a single chain, two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is an activation marker for human granulocytes.
Background References:
- Oikawa,S. et al., 2000, Biochem Biophys Res Commun??278?(3):564-8.
- Lasa,A. et al., 2008, Ann Hematol??87?(3):205-11.
- Ramachandran P, et al., 2006, J. Proteome Res. 5 (6): 1493?503.
- Zhao L, et al., 2002, J. Immunol. Methods 270 (1): 27?35.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
1088
NCBI Official Name:
carcinoembryonic antigen-related cell adhesion molecule 8
NCBI Official Symbol:
CEACAM8
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
33 kDa
Protein Accession #:
NP_001807.2
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P31997