Fetuin B Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-312-0.1mg | 0.1mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
FETUB, Fetuin-B, 16G2, Gugu
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Fetuin-B (FETUB), a second member of the fetuin family in mammals, is also known as Fetuin-like protein IRL685, 16G2 and Gugu, which is expressed in liver and testis and contains 2 cystatin fetuin-B-type domains. FETUB is a protease inhibitor required for egg fertilization. FETUB is also required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). As a liver-derived plasma protein, FETUB is essential for fertilization.
Background References:
- Olivier E., et al., 2000, Biochem. J. 350:589-597.
- Dietzel E., et al., 2013, Dev. Cell 25:106-112.
- Muzny D.M., et al., 2006, Nature 440:1194-1198.
Buffer:
50 mM Tris, 150 mM NaCl,pH8.0
Fusion Tag:
His Tag
NCBI Gene ID #:
26998
NCBI Official Name:
fetuin B
NCBI Official Symbol:
FETUB
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
42.4 kDa
Protein Accession #:
AAH69670
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9UGM5