SERPIND1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-381-0.05mg | 0.05mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
SerpinD1, HCF2, HLS2, HC-II
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Serpin D1 is also known as Heparin cofactor 2 (HCF2), Protease inhibitor leuserpin-2 (HLS2), Heparin cofactor II (HC-II), which belongs to the serpin family. HCF2 is expressed predominantly in liver. Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, SerpinD1 / HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). In a glycosaminoglycan-independent manner, serpinD1 / HC-II also inhibits chymotrypsin. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
Background References:
- van Deerlin V.M.D., et al., 1991, J. Biol. Chem. 266:20223-20231.
Buffer:
50 mM Tris, 150 mM NaCl, pH 7.5
Fusion Tag:
His Tag
NCBI Gene ID #:
3053
NCBI Official Name:
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
NCBI Official Symbol:
SERPIND1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
55.7 kDa
Protein Accession #:
AAH35028
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P05546