IL1R3 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-468-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
IL1RAP, IL-1RAcP, C3orf13, IL1R3
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
Background References:
- Huang J., et al., 1997, Proc. Natl. Acad. Sci. U.S.A. 94:12829-12832.
- Jensen L.E., et al., 2000, J. Immunol. 164:5277-5286.
- Smith D.E., et al., 2003, Immunity 18:87-96.
Buffer:
PBS, pH 7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
3556
NCBI Official Name:
interleukin 1 receptor accessory protein
NCBI Official Symbol:
IL1RAP
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
40 kDa
Protein Accession #:
Q9NPH3
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9NPH3