EGFR Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-263-0.05mg | 0.05mg | £765.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
EGFR, ERBB, ERBB1, HER1, PIG61, mENA
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
The epidermal growth factor receptor (EGFR; ErbB-1; HER1) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
Background References:
- Herbst RS, 2004, Int. J. Radiat. Oncol. Biol. Phys. 59 (2 Suppl): 21?6.
- Zhang H, et al.,2007, Journal of Clinical Investigation 117(8):2051-2058.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized mouse EGF at 10μg/ml can bind mouse EGFR with a linear range of 2. 5?1000 ng/mL.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
13649
NCBI Official Name:
epidermal growth factor receptor
NCBI Official Symbol:
Egfr
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
70 kDa
Protein Accession #:
Q01279-1
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q01279