Control Normal llama IgG1
| Code | Size | Price |
|---|
| PSI-XR-8002-0.5mg | 0.5mg | £437.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Llama
Antibody Isotype: IgG1
Antibody Clonality: Isotype Control
Regulatory Status: RUO
Application: Flow Cytometry
Storage:
Store vial at -20˚C prior to opening. Aliquot contents and freeze at -20˚C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable
Documents
Further Information
Application Note:
Llama IgG1 isotype control can be utilized as a control or standard reagent in Flow Cytometry, Western Blotting, and ELISA experiments where determination of sample isotype is important.
Background:
Comparative studies of old world camelids (Camelus bactrianus and Camelus dromedarius) and new world camelids (Lama pacos, Lama glama and Lama vicugna) have shown that heavy-chain-only immunoglobulins represent between 35% - 70% of total IgG in the sera of all species. Such antibodies are homodimers of heavy chains that lack the CH1 domain of conventional antibodies and therefore do not interact with light chains, exhibiting a lower molecular weight ~100 kDa. In llama and other species of camelids, these heavy-chain-only immunoglobulins belong to the IgG2 and IgG3 subclasses. All gamma chain camelid antibodies exhibiting the more conventional assembly of two light and two heavy chains with molecular weight ~150 kDa, belong to the IgG1 subclass.
Buffer:
0.075 M Tris, 0.375 M NaCl, 25% glycerol, 0.01% (w/v) Sodium Azide
Concentration:
1 mg/mL
Physical State:
Liquid
Predicted Molecular Weight:
398.4 . 96.1