IL-10 non-lytic Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-496-10ug | 10ug | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
Documents
Further Information
Additional Names:
Interleukin-10, Cytokine Sythesis Inhibitory Factor, CSIF
Application Note:
This recombinant proteins is for research use only.
Background:
Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.
Biological Activity:
Bioactivity demonstrated in cytokine synthesis inhibition assay, measuring inhibition of IL-6 production by PU5-1 cells.
Buffer:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 100 μl sterile water. Add 1X PBS to the desired protein concentration.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
3586
NCBI Official Name:
interleukin 10
NCBI Official Symbol:
IL10
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000563
Protein GI Number:
10835141
Purity:
>98% (SDS-PAGE).
Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
NS1 cells
Swissprot #:
P21581