NUCB2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-073-50ug | 50ug | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
Working aliquots are stable for up to 3 months when stored at -20˚C.
Documents
Further Information
Additional Names:
DNA-binding Protein NEFA, Nucleobindin-2, Nesfatin
Application Note:
This recombinant proteins is for research use only.
Background:
Nucelobindin-2 (NUCB2; Nesfatin-1) was first isolated in adipocytes, but is also expressed by gastric mucosa and pancreatic beta cells. This pattern of nucleobindin-2 expression, as well as the presence of nucelobindin-2 within the plasma of rodents and humans, strongly suggests that this compound may act as a circulating regulatory factor. Nucelobindin-2 is reported to reduce food intake after administration. It is responsible for regulating appetite and production of body fat. Excess nucelobindin-2 in the brain leads to a loss of appetite, lack of nesfatin-1 in the brain leads to an increase of appetite.
Buffer:
0.2um-filtered solution in PBS, pH 7.2.
Fusion Tag:
His Tag
NCBI Gene ID #:
53322
NCBI Official Name:
nucleobindin 2
NCBI Official Symbol:
Nucb2
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P81117
Protein GI Number:
17380456
Purity:
>90% (SDS-PAGE).
Endotoxin level is less than 1EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q9BY76