CD54 [ICAM-1] non-lytic Recombinant Protein

ProSci
Product Code: PSI-90-397
Product Group: Recombinant Proteins
Supplier: ProSci

CodeSizePrice
PSI-90-397-50ug50ug£469.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Mouse
Storage:
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.

Documents

Further Information

Additional Names:
ICAM1, Intercellular Adhesion Molecule 1
Application Note:
This recombinant proteins is for research use only.
Background:
Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1beta and LPS. Soluble CD54 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation.
Biological Activity:
Shows the biological function of the CD54 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
Buffer:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μg/ml in sterile PBS.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
15894
NCBI Official Name:
intercellular adhesion molecule 1
NCBI Official Symbol:
Icam1
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
AAH08626
Protein GI Number:
14250387
Purity:
>98% (SDS-PAGE).

Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
CHO cells
Swissprot #:
Q9Y6W8