4-1BB Recombinant Protein

Product Code: PSI-92-374

Supplier: ProSci

Code	Size	Price

PSI-92-374-0.05mg

0.05mg

£613.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Mouse

Storage:

Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Datasheet

Further Information

Additional Names:

Secreted CD137 antigen , Tumor necrosis factor receptor superfamily member 9 , Tnfrsf9, TNFRSF9, CD137

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.

Buffer:

Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Fusion Tag:

C-Fc tag

NCBI Gene ID #:

21942

NCBI Official Name:

tumor necrosis factor receptor superfamily, member 9

NCBI Official Symbol:

Tnfrsf9

NCBI Organism:

Mus musculus

Physical State:

Liquid

Predicted Molecular Weight:

44.7 kD

Protein Accession #:

P20334

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

Human Cells

Swissprot #:

P20334