5'-Nucleotidase Recombinant Protein

ProSci
Product Code: PSI-92-401
Product Group: Recombinant Proteins
Supplier: ProSci

CodeSizePrice
PSI-92-401-0.05mg0.05mg£883.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Mouse
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
5'-nucleotidase, Ecto-5'-nucleotidase, CD73, 5'-NT, NT5E
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Mouse CD73 is a glycosyl phosphatidylinositol (GPI) anchored membrane protein that belongs to the 5'-nucleotidase family. CD73 is an ecto 5'Nucleotidase expressed by most cell types. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 is a lymphocyte maturation marker that has functions independent of its catalytic activity. CD73 is also a regulator of leukocyte extravasation, a function that requires its 5'Nucleotidase activity.CD73 has also been reported to regulate expression of pro-inflammatory molecules in mouse endothelium.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 120mM NaCl,4mM CaCl2, 20% Glycerol, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
23959
NCBI Official Name:
5' nucleotidase, ecto
NCBI Official Symbol:
Nt5e
NCBI Organism:
Mus musculus
Physical State:
Liquid
Predicted Molecular Weight:
58.8 kD
Protein Accession #:
Q61503
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q61503