NTAQ1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-92-506-0.05mg | 0.05mg | £673.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Documents
Further Information
Additional Names:
Protein N-terminal glutamine amidohydrolase, WDYHV1, Protein NH2-terminal glutamine deamidase, N-terminal Gln amidase, Nt(Q)-amidase, C8orf32, NTAQ1, REF: C1009
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene, belongs to the NTAQ1 family.WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, which is an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. However,it does not act on substrates with internal or C-terminal glutamine andnon-glutamine residues in any position. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
Buffer:
Supplied as a 0.2 um filtered solution of PBS,100mM GSH,1% TritonX-100,15% glycerol,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-GST tag
NCBI Gene ID #:
55093
NCBI Official Name:
WDYHV motif containing 1
NCBI Official Symbol:
WDYHV1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
49.8 kD
Protein Accession #:
Q96HA8
Protein GI Number:
530363504
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q96HA8