Cathepsin L Recombinant Protein

Product Code: PSI-91-898

Supplier: ProSci

Code	Size	Price

PSI-91-898-0.05mg

0.05mg

£838.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Mouse

Storage:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Documents

Datasheet

Further Information

Additional Names:

Cathepsin L1, Major excreted protein, p39 cysteine proteinase, Ctsl1, CTSL

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Mouse Cathepsin L is a lysosomal cysteine proteinase which is a member of the peptidase C1 family. This protein is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Cathepsin L plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.

Buffer:

Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Fusion Tag:

C-6 His tag

NCBI Gene ID #:

13039

NCBI Official Name:

cathepsin L

NCBI Official Symbol:

Ctsl

NCBI Organism:

Mus musculus

Physical State:

Lyophilized

Predicted Molecular Weight:

36.8 kD

Protein Accession #:

P06797

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

Human Cells

Swissprot #:

P06797