p18-INK4c Recombinant Protein

ProSci
Product Code: PSI-91-223
Product Group: Recombinant Proteins
Supplier: ProSci

CodeSizePrice
PSI-91-223-0.05mg0.05mg£838.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Documents

Further Information

Additional Names:
Cyclin-Dependent Kinase 4 Inhibitor C, Cyclin-Dependent Kinase 6 Inhibitor, p18-INK4c, p18-INK6, CDKN2C, CDKN6
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in skeletal muscle, pancreas, and heart. CDKN2C inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB and prevent the activation of the CDK kinases. Studies have been shown the roles of CDKN2C gene in regulating spermatogenesis, as well as in suppressing tumorigenesis.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
1031
NCBI Official Name:
cyclin-dependent kinase inhibitor 2C
NCBI Official Symbol:
CDKN2C
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
20.3 kD
Protein Accession #:
P42773
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P42773