Aldehyde Dehydrogenase 1-A1 Recombinant Protein

ProSci
Product Code: PSI-92-097
Product Group: Recombinant Proteins
Supplier: ProSci

CodeSizePrice
PSI-92-097-0.05mg0.05mg£673.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
Retinal Dehydrogenase 1, RALDH 1, RalDH1, ALDH-E1, ALHDII, Aldehyde Dehydrogenase Family 1 Member A1, Aldehyde Dehydrogenase Cytosolic, ALDH1A1, ALDC, ALDH1, PUMB1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Aldehyde Dehydrogenase Family 1 Member A1 (ALDH1A1) is a cytoplasmic enzyme that belongs to the Aldehyde Dehydrogenase family. ALDH1A1 is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties and subcellular localizations. ALDH1A1 is the main cytosolic isoform, which has a lower affinity for aldehydes than the mitochondrial enzyme. ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. It can convert/oxidize retinaldehyde to retinoic acid.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, pH8.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
216
NCBI Official Name:
aldehyde dehydrogenase 1 family member A1
NCBI Official Symbol:
ALDH1A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
57 kD
Protein Accession #:
P00352
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P00352