Methenyl-THF synthetase Recombinant Protein
| Code | Size | Price |
|---|
| PSI-92-280-0.05mg | 0.05mg | £883.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Documents
Further Information
Additional Names:
5-formyltetrahydrofolate cyclo-ligase, 5, 10-methenyl-tetrahydrofolate synthetase, MTHFS, Methenyl-THF synthetase
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM Tris,200mM Nacl,1mM DTT,50% Glycerol,pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
10588
NCBI Official Name:
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NCBI Official Symbol:
MTHFS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
24.3 kD
Protein Accession #:
P49914
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P49914