IL-18 binding protein Recombinant Protein

Product Code: PSI-91-814

Supplier: ProSci

Code	Size	Price

PSI-91-814-0.05mg

0.05mg

£373.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Human

Storage:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Documents

Datasheet

Further Information

Additional Names:

Interleukin-18-binding protein, Tadekinig-alfa and IL18BP, IL-18BP

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Interleukin-18-binding protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mononuclear cells. IL18BP functions as an IL18 inhibitor. IL18BP binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. It has been shown that IL18BP may be a promising molecular approach to inhibit neointimal hyperplasia and arteriosclerosis progression following coronary and peripheral angioplasty.

Buffer:

Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Fusion Tag:

C-Fc tag

NCBI Gene ID #:

10068

NCBI Official Name:

interleukin 18 binding protein

NCBI Official Symbol:

IL18BP

NCBI Organism:

Homo sapiens

Physical State:

Lyophilized

Predicted Molecular Weight:

44.7 kD

Protein Accession #:

O95998

Protein GI Number:

530384410

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

Human Cells

Swissprot #:

O95998