BMS-3
| Code | Size | Price |
|---|
| AG-CR1-2901-M005 | 5 mg | £80.00 |
Quantity:
| AG-CR1-2901-M025 | 25 mg | £290.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Storage:
Short Tem: +4°C Long Term: -20°C
Documents
Further Information
Alternate Names/Synonyms:
N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2- yl)cyclopropanecarboxamide
Appearance:
Off-white solid.
CAS:
1338247-30-5
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.
InChi:
InChI=1S/C17H12Cl2F2N4OS/c18-9-2-1-3-10(19)14(9)25-12(6-11(24-25)15(20)21)13-7-22-17(27-13)23-16(26)8-4-5-8/h1-3,6-8,15H,4-5H2,(H,22,23,26)
InChiKey:
YBGGBHCJSAEIAS-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1338247-30-5. Formula: C17H12Cl2F2N4OS. MW: 429.3. Potent LIMK (Lim kinase) inhibitor. Has IC50 values of 5nM and 6nM for LIMK1 and LIMK2, respectively.
MDL:
MFCD17019326
Molecular Formula:
C17H12Cl2F2N4OS
Molecular Weight:
429.3
Package Type:
Vial
Product Description:
Potent LIMK (Lim kinase) inhibitor. Has IC50 values of 5nM and 6nM for LIMK1 and LIMK2, respectively.
Purity:
>98% (HPLC)
SMILES:
ClC1=C(N2C(C3=CN=C(NC(C4CC4)=O)S3)=CC(C(F)F)=N2)C(Cl)=CC=C1
Solubility Chemicals:
Soluble in DMSO (5mg/ml).
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Phenyl-substituted pyrimidine compounds useful as kinase inhibitors: S.T. Wrobelski, et al.; WO2006084017 (2006) | Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors: P. Ross-Macdonald, et al.; Mol. Cancer Ther. 7, 3490 (2008)