DYRK1 Inhibitor Negative Control AnnH79
| Code | Size | Price |
|---|
| AG-CR1-3652-C500 | 500 ug | £140.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Storage:
Short Term: +4°C. Long Term: -20°C
Documents
Further Information
Alternate Names/Synonyms:
2-(1-Bromo-7,8-dichloro-9H-pyrido[3,4-b]indol-9-yl)acetonitrile; AnnH79
Appearance:
Off-white to pale yellow solid.
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light and moisture.
Hazards:
H319
InChi:
InChI=1S/C13H6BrCl2N3/c14-13-12-8(3-5-18-13)7-1-2-9(15)10(16)11(7)19(12)6-4-17/h1-3,5H,6H2
InChiKey:
VJUNHKYSEMGQTK-UHFFFAOYSA-N
Long Description:
Chemical. Formula: C13H6BrCl2N3. MW: 355.0. Synthetic. Inactive harmine analog that does not inhibit DYRK1A/DYRK1B. Useful as negative control for β-carboline analog DYRK1A/B inhibitors.
Molecular Formula:
C13H6BrCl2N3
Molecular Weight:
355
Other data:
DMSO Stock Solution: Prior to performing biological experiments the DMSO stock solution should be further diluted into water or other aqueous buffers to ensure that the residual amount of DMSO is insignificant, since DMSO may have physiological effects at high concentrations.
Package Type:
Plastic Vial
Precautions:
P305, P351, P338
Product Description:
Inactive harmine analog that does not inhibit DYRK1A/DYRK1B. Useful as negative control for beta-carboline analog DYRK1A/B inhibitors.
Purity:
>98% (HPLC, NMR)
Signal Word:
Warning
SMILES:
ClC1=CC=C2C(N(CC#N)C3=C2C=CN=C3Br)=C1Cl
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Selectivity profiling and biological activity of novel beta-carbolines as potent and selective DYRK1 kinase inhibitors: K. R?ben, et al.; PLos One 10, e0132453 (2015)