BTN3A1 Recombinant Protein

ProSci
Product Code: PSI-96-835
Product Group: Recombinant Proteins
Supplier: ProSci

CodeSizePrice
PSI-96-835-0.1mg0.1mg£686.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

Documents

Further Information

Additional Names:
BTN3A1,CD277,BTF5
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.
Background References:
  • Yamashiro H., et al., 2010, J. Leukoc. Biol. 88:757-767.
  • Messal N., et al., 2011, Eur. J. Immunol. 41:3443-3454.
  • Harly C., et al., 2012, Blood 120:2269-2279.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
11119
NCBI Official Name:
Butyrophilin, subfamily 3, member A1
NCBI Official Symbol:
BTN3A1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
50.8 kDa
Protein Accession #:
AAI21801
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O00481