Further Information
Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150, CD11c, ITGAX, CD11C
Flow Cytometry: 0.5-1 ug/million cells
IF: 0.5-1 ug/ml
Functional Activity (Blocking): order BSA/azide free format
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11c antibody to be titered up or down for optimal performance.
CD11c, also known as Integrin alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
0.2 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Human monocytic U937 phorbol ester-treated cells were used as the immunogen for this CD11c antibody.
3687
integrin, alpha X (complement component 3 receptor 4 subunit)
ITGAX
Homo sapiens
Liquid
Protein G affinity chromatography
Immunology,Signal Transduction
P20702
Optimal dilutions for each application to be determined by the researcher
