Welcome to ProSci - Distributed in the UK & Ireland by Caltag Medsystems

ProSci

ProSci a broad catalogue of over 30,000 research antibodies and has completed over 20,000 Custom Antibody projects.

Their in-house labs and animal facilities (USDA licensed and NIH/OLAW approved) provide an extensive array of antibody products & services, with a focus on providing the highest quality monoclonal, polyclonal, and single domain antibodies.

ProSci's expertise in antibody production, immunochemistry services, and biological research is realised through customisable services, innovative products, competitive pricing, high-quality research tools, and unparalleled technical support.

Established in 1998, ProSci is a reliable partner with over 20 years of serving the research community globally.

Antibodies

ProSci specialises in the production of affinity-purified peptide-specific antibodies to novel antigens in fields such as HIV, Apoptosis, Signal Transduction, Neurobiology, Autophagy, and Immunology.

Affinity-purification allows for the isolation of antibodies specific to the epitope of interest. This results in ProSci's polyclonal antibodies having the same specificity as monoclonal antibodies at a competitive price.

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Single Domain Antibodies

ProSci's Single Domain Antibody products are highly valuable in fundamental research, diagnostic, and therapeutic applications.

Single Domain Antibodies (sdAbs), also known as VHH antibodies or nanobodies, are isolated from camelid heavy chain only antibodies and are comprised of only the variable domain. As such, they lack light chains, are smaller and more stable compared to conventional antibodies, yet possess fully functional antigen-binding capability.

Due to their size (approximately 15 kDa) and their longer CDR3 region, a single domain antibody is adept at reaching otherwise inaccessible epitopes that may play a crucial role in the molecular mechanisms of disease.

Single Domain Antibodies - Podcast

Single Domain Antibodies - Video

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Research Grade Biosimilars

Beyond therapeutics, monoclonal antibodies (mAbs) shown to be effective in the clinic can help to facilitate laboratory research.

mAbs, also known as biosimilars, are useful tools to research novel therapies and uncover effective off-target applications.

With known and approved data on toxicity and efficacy, these biologics are used as benchmarks to accelerate findings from bench to clinic.

ProSci has more than 800 research-grade biosimilar antibodies available in the following research areas:

See all Research Grade Biosimilars

Recombinant Proteins & Peptides

ProSci's recombinant proteins are available as monomers, dimers, trimers, and multimers.

Full-length and partial-length proteins are available for control experiments, assay development, and antibody development projects.

Utilisation of E. coli, mammalian, yeast, and baculovirus expression systems with various activity assays have been performed to ensure functionality.

Applications of ProSci's recombinant proteins include CLIA, EIA, IM, Lateral Flow, and WB.

As well as recombinant proteins, ProSci also provides peptides. Match one of ProSci's peptides with a primary antibody for blocking and control experiments.

See all Recombinant Proteins     See all Peptides

Research Areas

ProSci also provides products for the following research areas:

Other Products

ProSci also offers a complete assortment of cell & tissue lysates, antibiotics & antimicrobials, isotype controls, and more to complement the use of their antibodies, peptides, and recombinant proteins.

See all ProSci's Other Products

ProSci Custom Antibody Services

High-quality technical assistance, competitive pricing, and highly customisable projects qualify ProSci staff as experts in custom antibody development & production.

The value and convenience of ProSci's custom antibody production services are further advanced with a complete spectrum of available immunochemistry services. These include (but are not limited to) antigen design assistance, peptide synthesis, protein conjugation, and immunisation.

Caltag Medsystems is here with you every step of the way to support your custom antibody project with ProSci.

ProSci custom antibody services include:

ProSci Support

For further ProSci information, please visit prosci-inc.com.

To find informative antibody protocols, downloadable content, and other reference materials, please visit Application & Techniques.

Blog posts

Enhance your Research with ProSci’s Polyclonal Antibody Services

At ProSci, custom polyclonal antibodies are generated in various host species from customised immunogens designed by expert antibody scientists.

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The Role of Monoclonal Antibodies & Biosimilars in Research

ProSci has more than 800 research-grade biosimilar antibodies in their catalogue and a team of custom antibody specialists providing expertise.

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Does Your Research Require High-Quality and Consistent Rabbit Recombinant Antibodies?

ProSci offers a suite of services to develop rabbit recombinant antibodies with a defined structure, providing highly consistent & specific antibodies.

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Immune Checkpoints

ProSci offers reagents that can be used to study the actions of multiple immune checkpoint proteins such as CTLA-4, PD-1, & its ligands PD-L1 & PD-L2.

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Viral Infectious Diseases

To support research & studies into infectious diseases, ProSci has reagents for the study of many viral disease agents inc. Covid, HIV, & Influenza.

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SARS-CoV-2 (COVID-19) Mutations

As viruses create more of themselves, they mutate - single-point changes in genetic code. SARS-CoV-2 virus mutated to be more transmissible.

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What is Cytokine Storm? - Cytokine Storm and COVID-19

The cytokine storm is a relatively new discovery & is actively being studied. ProSci offers cytokine & chemokine antibodies & recombinant proteins.

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Immune Evasion of SARS-CoV-2

Research continues in understanding mechanisms of SARS-CoV-2 immune evasion. ProSci offers antibodies & recombinant proteins for SARS-CoV-2 research.

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SARS-CoV-2 Open Reading Frames (ORFs)

The SARS-CoV-2 genome is ~29 kb divided into 10 ORFs. Each of these ORFs (except seemingly ORF10) is translated in 29 different proteins.

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SARS-CoV-2 Recombinant Virus Lineages

ProSci has developed SARS-CoV-2 variant-specific reagents by focusing on unique point mutations in the spike protein.

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The Role of Monoclonal Antibodies & Biosimilars in Life Science Research

mAbs (biosimilars) as tools to research novel new therapies and uncover effective off-target application.

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Insights into the Molecular Mechanisms Regulating Necroptosis 

This white paper details findings in molecular mechanisms that govern necroptosis related to RIPK & details #2283 use to analyse expression of RIPK3.

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Exploring the Roles of RIPKs in Immune Responses, Inflammation, and Cell Death: Recent Findings 

ProSci has 25+ years expertise in developing antibodies. This white paper details use of RIPK antibodies & findings on RIPKs in signalling pathways.

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A Deep Dive into the Hidden Power of Programmed Cell Death: Unlocking Therapeutic Potential with Antibodies 

ProSci has 25+ years of expertise in developing antibodies. This white paper details use of ProSci antibodies in the study of programmed cell death.

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PD-1: Expanding Beyond Cancer Research

ProSci details the importance of PD-1 antibodies are important in resolving complex interactions between the immune system & pathological conditions.

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Research Grade Biosimilar Antibodies from ProSci

Therapeutic antibodies dominate pipelines and top selling drugs at major pharmaceutical companies. They have proven to be valuable tools in the f…

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