NSJ Bioreagents

MSK1 Antibody (pS376)

Product Code:
 
NSJ-RQ4786
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
FCF-18
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store the phospho-MSK1 antibody at -20°C.
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Western blot testing of lysate from human HEK293 cells, treated with EGF, with phospho-MSK1 antibody. Predicted molecular weight ~90 kDa.
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Western blot testing of lysate from human HEK293 cells, treated with EGF, with phospho-MSK1 antibody. Predicted molecular weight ~90 kDa.

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NSJ-RQ4786-100ul100ul£535.00
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Further Information

Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the phospho-MSK1 antibody should be determined by the researcher.
Description:
'Mitogen and stress activated protein kinase 1,' also called RPS6KA5, is a serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. [UniProt]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human MSK1 / RPS6KA5 (surrounding pS376) was used as the immunogen for the phospho-MSK1 antibody.
Limitation:
This phospho-MSK1 antibody is available for research use only.
Localization:
Nuclear + cytoplasmic
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
O75582