RIG-I Antibody / DDX58

Western blot: 1:500-1:1000

Optimal dilution of the RIG-I antibody should be determined by the researcher.

Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN.

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human RIG-I was used as the immunogen for the RIG-I antibody.

This RIG-I antibody is available for research use only.

Affinity purified

Human

O95786