NSJ Bioreagents

EIF4E Antibody

Product Code:
 
NSJ-RQ5157
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
AFHI-5
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store the EIF4E antibody at -20°C.
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Western blot testing of human HEK293 cell lysate with EIF4E antibody. Predicted molecular weight ~27 kDa.
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Western blot testing of human HEK293 cell lysate with EIF4E antibody. Predicted molecular weight ~27 kDa.

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NSJ-RQ5157-100ul100ul£535.00
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Further Information

Application Details :
Western blot: 1:100-1:5000
Application Note:
Optimal dilution of the EIF4E antibody should be determined by the researcher.
Description:
eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human EIF4E was used as the immunogen for the EIF4E antibody.
Limitation:
This EIF4E antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P06730