Further Information
ST14, HAI, MT-SP1, MTSP-1, MTSP1, PRSS14, SNC19, TADG-15, TADG15, TMPRSS14
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 566-855 of human ST14 (NP_068813.1).
6768
suppression of tumorigenicity 14 (colon carcinoma)
ST14
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 100kDa
Affinity purification
Other
Q9Y5Y6
Optimal dilutions for each application to be determined by the researcher.