Further Information
KOR-3, NOCIR, NOP, NOPr, OOR, ORL1, nociceptin receptor, kappa-type 3 opioid receptor, kappa3-related opioid receptor, nociceptin/orphanin FQ receptor, opiate receptor-like 1, orphanin FQ receptor
WB: 1:500 - 1:2000
The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
A synthetic peptide of human OPRL1
4987
opioid related nociceptin receptor 1
OPRL1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 50kDa
Affinity purification
Neuroscience, Obesity, Signal Transduction
P41146
Optimal dilutions for each application to be determined by the researcher.