Further Information
MYO5A, MYR12, myoxin, myosin, heavy polypeptide kinase, myosin VA (heavy chain 12, myoxin), myosin VA, myosin V, MYO5, MYH12, GS1, dilute
WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:100
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 950-1150 of human MYO5A (NP_000250.3).
4644
myosin VA (heavy chain 12, myoxin)
MYO5A
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 240kDa
Affinity purification
Cell Cycle, Neuroscience, Signal Transduction
Q9Y4I1
Optimal dilutions for each application to be determined by the researcher.