ProSci

VAP-1 Recombinant Protein

Product Code:
 
PSI-40-576
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Hamster
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
blue ice or RT
Storage:
 
The lyophilized VAP-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted VAP-1 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing VAP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
 

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CodeSizePrice
PSI-40-576-0.002mg0.002mg£300.00
Quantity:
PSI-40-576-0.01mg0.01mg£428.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
HPAO, SSAO, VAP1, VAP-1, Membrane primary amine oxidase, Copper amine oxidase
Background:
VAP-1 is a type II membrane cell adhesion protein belonging to the copper/topaquinone oxidase family. It is primarily expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. VAP-1 can catalyze the oxidative deamination of low molecular weight amines, and plays an important role in the migration of lymphocytes to inflamed tissue. Inhibition of VAP-1 can protect against inflammation related damage to certain injured tissues. Additionally, VAP-1 can function as a significant prognostic marker for certain cancers and cardiovascular diseases. Recombinant VAP-1 is a mixture of monomeric and disulfide linked homodimeric forms of a 737 amino acid polypeptide corresponding to amino acids 27 to 763 of the VAP-1 precursor.
Biological Activity:
Biological activity was measured by its ability to produce hydrogen peroxide during the oxidation of benzylamine. The specific activity >16 pMoles/min/μg of VAP-1. Endotoxin level is less than 0.1 ng per μg of VAP-1 (1EU/μg).
NCBI Gene ID #:
8639
NCBI Official Name:
amine oxidase, copper containing 3
NCBI Official Symbol:
AOC3
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001264660.1
Protein GI Number:
480306390
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
CHO cells
Swissprot #:
Q16853

Documents