NSJ Bioreagents

Aurora B Antibody / AURKB

Product Code:
 
NSJ-V3927
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
ARRK2-1
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Store the AURKB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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IHC testing of FFPE human prostate tissue with AURKB antibody (clone ARRK2-1). HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
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IHC testing of FFPE human prostate tissue with AURKB antibody (clone ARRK2-1). HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.

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CodeSizePrice
NSJ-V3927-20UG20 ug£264.00
Quantity:
NSJ-V3927-100UG100 ug£534.00
Quantity:
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Further Information

Application Details :
IHC (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Optimal dilution of the AURKB antibody should be determined by the researcher.
Description:
Aurora B is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. [UniProt]
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
Amino acids 89-251 were used as the immunogen for this AURKB antibody.
Limitation:
This AURKB antibody is available for research use only.
Localization:
Nuclear, cytoplasmic
Purity:
Protein G affinity
Species Reactivity :
Human
Uniprot #:
Q96GD4