NSJ Bioreagents

MUC1 Antibody

Product Code:
 
NSJ-F40466
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot the MUC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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MUC1 antibody western blot analysis in MDA-MB435 lysate. Predicted molecular weight: 120-500 kDa depending on glycosylation level
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MUC1 antibody western blot analysis in MDA-MB435 lysate. Predicted molecular weight: 120-500 kDa depending on glycosylation level

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CodeSizePrice
NSJ-F40466-0.08ML0.08 ml£260.00
Quantity:
NSJ-F40466-0.4ML0.4 ml£502.00
Quantity:
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Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the MUC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The MUC1 alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. [UniProt]
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 1202-1231 from the human protein was used as the immunogen for this MUC1 antibody.
Limitation:
This MUC1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P15941