NSJ Bioreagents

PAK6 Antibody

Product Code:
 
NSJ-F50895
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot the PAK6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot analysis of PAK6 antibody in lysate from transiently transfected COS7 cells. Lane 1: negative control, 2: PAK1, 3: PAK2, 4: PAK4, 5: PAK5, and 6: PAK6-expressing cells.
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Western blot analysis of PAK6 antibody in lysate from transiently transfected COS7 cells. Lane 1: negative control, 2: PAK1, 3: PAK2, 4: PAK4, 5: PAK5, and 6: PAK6-expressing cells.

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CodeSizePrice
NSJ-F50895-0.08ML0.08 ml£260.00
Quantity:
NSJ-F50895-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the PAK6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The PAK6 protein shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. PAK6 was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 116-146 from the human protein was used as the immunogen for this PAK6 antibody.
Limitation:
This PAK6 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
Q9NQU5