NSJ Bioreagents

ILK2/ILK1 Antibody

Product Code:
 
NSJ-F40141
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot the ILK2/ILK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot analysis of ILK2/ILK1 antibody and HeLa lysate.~
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Western blot analysis of anti-ILK2/ILK1 antibody and mouse heart tissue lysate
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Western blot analysis of ILK2/ILK1 antibody and HeLa lysate.~
Western blot analysis of anti-ILK2/ILK1 antibody and mouse heart tissue lysate

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CodeSizePrice
NSJ-F40141-0.08ML0.08 ml£260.00
Quantity:
NSJ-F40141-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the ILK2/ILK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) is an ankyrin repeat containing 51 kDa receptor-proximate serine-threonine kinase (1), with a reported migration rate of 59K. This 451 amino acid protein interacts with the cytoplasmic domain of the beta-1 integrin subunit and contains sequence motifs found in pleckstrin homology domains capable of interacting with phosphoinositide lipids. ILK is an upstream regulator of Pi(3)K dependant activation of protein kinase B (PKB/AKT) and inhibition of glycogen synthase kinase 3 (GSK-3). ILK2 expression is associated with mediation of cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. ILK2 is overexpressed in some highly invasive tumor cell lines.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 391-421 from the human protein was used as the immunogen for this ILK2/ILK1 antibody.
Limitation:
This ILK2/ILK1 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human, Mouse
Species Reactivity (Predicted):
Rat, Bovine
Uniprot #:
Q13418