NSJ Bioreagents

CYLD Antibody

Product Code:
 
NSJ-N1164
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the CYLD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of human samples with CYLD antibody at 2ug/ml. Predicted molecular weight ~107kDa.
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Western blot testing of human samples with CYLD antibody at 2ug/ml. Predicted molecular weight ~107kDa.

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CodeSizePrice
NSJ-N1164-25UG25 ug£254.00
Quantity:
NSJ-N1164-100UG100 ug£450.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Western blot: 2-5ug/ml
Application Note:
Provided assay concentrations are suggestions only, CYLD antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
1540
Immunogen:
A recombinant protein fragment from the N-termiinal region of human CYLD was used as the immunogen for this antibody.
Limitation:
This CYLD antibody is available for research use only.
Purity:
Protein A affinity chromatography
Species Reactivity :
Human, Mouse