NSJ Bioreagents

DC-SIGN Antibody

Product Code:
 
NSJ-N1090
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the DC-SIGN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
1 / 1
Western blot testing of human samples with DC-SIGN antibody at 2ug/ml. Predicted molecular weight ~46 kDa.
❮❯

Western blot testing of human samples with DC-SIGN antibody at 2ug/ml. Predicted molecular weight ~46 kDa.

No additional charges, what you see is what you pay! *

CodeSizePrice
NSJ-N1090-25UG25 ug£254.00
Quantity:
NSJ-N1090-100UG100 ug£450.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Application Details :
Western blot: 2-5ug/ml
Application Note:
Provided assay concentrations are suggestions only, DC-SIGN antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
DC-SIGN (Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin) also known as CD209, is part of the Lectin family of proteins. DC-SIGN is part of the innate immune response via its modulation of Toll-like Receptors. It is present on the surface of macrophages and dendritic cells and binds mannose carbohydrates, a class of PAMPS found on bacteria, fungi and viruses. PAMP stimulated DC-SIGN activates the Raf kinases Raf-1 and B-Raf. Raf-1 phosphorylates Ser276 of NF-kB p65 which serves as a binding site for histone acetyltransferases CREB-binding protein (CBP) and p300. Acetylation of NF-kB p65 leads to enhanced and prolonged anti-inflammatory cytokine IL-10 production.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
30835
Immunogen:
A recombinant protein fragment from human DC-SIGN was used as the immunogen for this antibody.
Limitation:
This DC-SIGN antibody is available for research use only.
Purity:
Protein A purified antibody
Species Reactivity :
Human, Mouse