NSJ Bioreagents

SIN1 Antibody

Product Code:
 
NSJ-N1067
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Canine (dog)
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Aliquot and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.
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Western blot testing of human samples with SIN1 antibody at 1ug/ml.
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Western blot testing of human samples with SIN1 antibody at 1ug/ml.

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CodeSizePrice
NSJ-N1067-25UG25 ug£254.00
Quantity:
NSJ-N1067-100UG100 ug£450.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Western blot: 1-3ug/ml
Application Note:
Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
mTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
79109
Immunogen:
A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
Limitation:
This SIN1 antibody is available for research use only.
Purity:
Protein A purified antibody
Species Reactivity :
Human, Mouse, Rat, Dog