Leinco Technologies

Anti-Human DDX3 (NT)

Product Code:
 
LEI-D326
Product Group:
 
Primary Antibodies
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
Ambient
Storage:
 
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
 

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CodeSizePrice
LEI-D326-20ug20 ug£199.00
Quantity:
LEI-D326-0.1mg0.1 mg£591.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Formulation:
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Long Description:
DDX3 contains all of the motifs of the DEAD-box family of RNA helicases, including the Asp-Glu-Ala-Asp sequence that gives the protein family its name and distinguishes it from other RNA helicases.1,2 DDX3 is localized to the X chromosome and has a highly conserved functional homolog (DBY) on the Y chromosome.3 DDX3 is thought to be involved in RNA splicing, RNA transport, and translation initiation.4 It has also been shown to be involved in cell growth control and is deregulated in hepatitis virus-associated hepatocellular carcinoma. Recent experiments suppressing DDX3 expression blocked HIV-1 RNA export from the nucleus, suggesting that DDX3 functions as a shuttling protein that transports the HIV-1 protein Rev and its cofactor CRM1 from the nucleus to the cytoplasm.
Target:
DDX3

References

1. Linder, P. et al. (1989) Nature 337:121 2. Park, S. H. et al. (1998) Cytogenet. Cell Genet. 81:178 3. Lahn, B. T. et al. (1997) Science 278:675 4. Abdelhaleem, M. (2005) Clin. Biochem. 38:499