Leinco Technologies

IL-27 (Intermediate Domain) Blocking Peptide

Product Code:
 
LEI-I-512
Product Group:
 
Peptides
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
 

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LEI-I-512-50ug50 ug£216.00
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Concentration:
0.2 mg/ml
Format:
This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Formulation:
This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Long Description:
Interleukin-27 (IL-27) is a novel IL-12 family member that plays a role in the early regulation of T helper cell 1 initiation, including induction of T-bet and IL-12 receptor beta 2 expression.1 IL-27 is produced by antigen-presenting cells2 and plays an important function in regulating the activity of B and T lymphocytes.3 IL27 may be a potential therapeutic agent against rheumatoid arthritis (RA) at the onset of the disease.4
Target:
Interleukin-27

References

1. Yoshimoto T et al. (2004) Cancer Res. 64: 1152 2. De Sauvage FJ et al. (2003) Proceedings of the National Acad of Sci of USA 100: 15047 3. Devergne O et al. (2006) J Immunol. 176: 5890 4. Liew FY et al. (2008) Ann Rheum Dis. 67: 1474