Leinco Technologies

Anti-Human Flt-3 Ligand (Clone 40406)

Product Code:
 
LEI-F1071
Product Group:
 
Primary Antibodies
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
40406
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Neutralisation
  • Western Blot (WB)
Shipping:
 
Ambient
Storage:
 
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
 

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CodeSizePrice
LEI-F1071-500ug500 ug£694.00
Quantity:
LEI-F1071-25ug25 ug£967.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Formulation:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen:
Purified Recombinant Human Flt-3 Ligand (Accession # AAA17999)
Long Description:
Fms-related tyrosine kinase 3 ligand (FLT3LG) is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor (SCF) and colony stimulating factor 1 (CSF-1). In synergy with other growth factors, such as IL-7 and IL-3, Flt-3 ligand promotes long-term expansion and differentiation of human pro-B-cells.1,2 Flt3 ligand is a cytokine capable of inducing large numbers of dendritic cells that dramatically enhances the sensitivity of antigen-specific B and T cell responses to systemic injection of a soluble protein. Through a CD40-CD40 ligand-dependent mechanism Flt-3 Ligand influences the class of antibody produced and enables productive immune responses.3
Target:
Flt-3 Ligand

References

1. Mattson, J. et al. (1994) Nature 368: 643 2. Cleveland, LS. et al. (1995) Oncogene 10: 149 3. Maliszewski, CR. et al. (1998) J. Exp. Med. 188: 2075