Leinco Technologies

Anti-Human CD119 (IFN-γ Rα Chain)

Product Code:
 
LEI-I-600
Product Group:
 
Primary Antibodies
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Neutralisation
  • Western Blot (WB)
Shipping:
 
Ambient
Storage:
 
The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
 

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CodeSizePrice
LEI-I-600-25ug25 ug£375.00
Quantity:
LEI-I-600-100ug100 ug£648.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Antigen Distribution:
The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
Conjugate/Tag/Label:
Antigen Affinity Purified
Immunogen:
NS0-Derived Mouse IFN-γ R1 Extracellular Domain
Long Description:
IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and β chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
NCBI Gene:
15979
Target:
IFNγ Rα

References

1. Calderon, J. et al. (1988) PNAS 85:4837 2. Garcia-Sastre, A. et al. (2002) Int. Rev. Immunol. 21:305 3. Fish, E. et al. (2002) J. Interferon Cytokine Res. 22:835