Leinco Technologies

Anti-Mouse CD25 - Purified (PhenoCycler-Fusion (CODEX)® Ready)

Product Code:
 
LEI-C526
Product Group:
 
Primary Antibodies
Host Type:
 
Rat
Antibody Isotype:
 
IgG1 λ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
PC61
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Spatial Biology
Shipping:
 
Ambient
Storage:
 
This antibody is stable for at least one week when stored at 2-8°C. For long term storage aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
 

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LEI-C526-50ug50 ug£167.00
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This product comes from: US.
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Further Information

Antigen Distribution:
CD25 is expressed in activated T cells and B cells, thymocyte subset, pre-B cells, T regulatory cells.
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified (PhenoCycler® Ready)
Format:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4.
Formulation:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4.
Immunogen:
IL-2-dependent cytolytic mouse T-cell clone B6.1
Long Description:
CD25, a 55 kD type I transmembrane glycoprotein, has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Many resting memory T cells constitutively express IL2RA. It functions as the receptor for HTLV-1, resulting in its expression on neoplastic cells in adult T cell lymphoma/leukemia. CD25 (sIL-2R) has been used to track disease progression. Some additional clinical applications include Chagas disease, a disease characterized by a decline of CD25 expression on immune cells, and Multiple sclerosis, in which treatments with mAbs target CD25.
NCBI Gene:
16184
Target:
CD25

References

1. Warren J. Leonard et al. (2002) The EMBO Journal 21: 3051 2. FW Alt et al. (1995) Immnnity 3: 521 3. Greene WC et al. (1990) J Invest Dermatol. 94: 27S