MBL

Anti-IGFBP1 (Human) mAb

Product Code:
 
MBL-W029-3
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2b κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
2B9-2
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
-20°C
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MBL-W029-3100 ul£323.00
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  • Further Information
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Further Information

Applications:
FCM - 1-10 ug/mL
Background:
IGFBP1, also known as placental protein 12 (PP12), is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin domain. IGFBP1 circulates in the plasma and has been shown to either inhibit or stimulate the growth promoting effects of its ligands called insulin-like growth factors (IGFs) I and II. High expression levels of IGFBP1 have been implicated in metastasis of prostate cancer.
Formulation:
1 mg/mL in PBS/50% glycerol, pH 7.2
Gene IDs:
Human: 3438
Immunogen Translated:
Human IGFBP1 expressed Ba/F3transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity:
This antibody reacts with human IGFBP1 on Flow cytometry.
Source:
This antibody was purified from hybridoma culture supernatant by Protein A affinity column chromatography.
Target:
IGFBP1

Documents

References

1) Dolcini, L., et al., FEBS J. 276, 6033-6046 (2009) 2) Sala, A., et al., J. Biol. Chem. 280, 29812-29819 (2005) 3) Kojima, T and Kitamura, T. Nat. Biotechnol. 17, 487-490 (1999) 4) Jones, J. I., et al., J. Biol. Chem. 268, 1125-1131 (1993)