MBL

Anti-ADAMTS1 (Human) mAb

Product Code:
 
MBL-W080-3
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
2B9CB6
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
-20°C
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MBL-W080-3100 ul£345.00
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  • Further Information
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Further Information

Applications:
FCM - 1-10 ug/mL
Background:
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) is a member of the ADAMTS protein family. ADAMTS1 is a secreted protein that has an N-terminal signal peptide, a zinc metalloprotease domain containing a zinc-binding site, and a cysteine-rich region containing two putative disintegrin loops. It is located in the extracellular matrix and functions as an active metalloprotease that may be associated with various inflammatory processes. Overexpression of ADAMTS1 is found in metastatic carcinoma.
Formulation:
1 mg/mL in PBS/50% glycerol, pH 7.2
Gene IDs:
Human: 9510
Immunogen Translated:
Human ADAMTS1 expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity:
This antibody reacts with human ADAMTS1 on Flow cytometry.
Source:
This antibody was purified from hybridoma culture supernatant by Protein A affinity column chromatography.
Target:
ADAMTS1 (Human)

Documents

References

1) Gerhardt, S., et al., J. Mol. Biol. 373, 891-902 (2007) 2) Cal, S., et al., Gene 283, 49-62 (2002) 3) Kojima, T. and Kitamura,T., Nat. Biotechnol. 17, 487-490 (1999) 4) Kuno, K., et al., J. Biol. Chem. 272, 556-562 (1997)