MBL

Anti-CD14 (Human) mAb-APC

Product Code:
 
MBL-FP10348010
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1 κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
61D3
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP10348010100 tests£471.00
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Further Information

Background:
The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
Concentration:
5 uL (1 ug)/test
Conjugate:
APC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD14

Documents

References

Schlossman, S. F., Leukocyte typing V. Oxford University Press (1995) Nakamura, T., et al., J. Immunol. 151, 6933-6941 (1993) Alam, M. S., et al., J Infect Dis. 199, 494-504 (2009)