Elabscience

Recombinant Mouse Leptin

Product Code:
 
PKSM041419
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSM041419-10ug10ug£96.00
Quantity:
PKSM041419-50ug50ug£133.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
Leptin
Accession:
Q544U0
Background:
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level. When mutations are introduced in obese gene, mice with impaired function of leptin are massively obese and in high risk of diabetes. Leptin deficiency reduces metablic rate. Leptin deficient mice are less active and with lower body temperature than normal animals. Human Leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin consists of 167 amino acid residue including a 21 amino acid residue signal sequence and 146 amino acid residue mature protein sequence.
Calculated MW:
16.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 300mM NaCl, pH7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
14 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Val22-Cys167
Target Synonym:
Leptin;Obese Protein;Obesity Factor;LEP;OB;OBS
UNIProt ID:
Q544U0

Documents