Elabscience

LSM10 Polyclonal Antibody

Product Code:
 
E-AB-52682
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using LSM10 Polyclonal Antibody at dilution of 1:100(?200)
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using LSM10 Polyclonal Antibody at dilution of 1:100(?200)

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E-AB-52682-20uL20uL£125.00
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E-AB-52682-60uL60uL£172.00
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E-AB-52682-120uL120uL£237.00
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E-AB-52682-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
LSM10
Background:
LSm10 (U7 snRNA-associated Sm-like protein LSm10) is a nuclear protein that belongs to the snRNP (small nuclear ribonucleoproteins) Sm protein family. The survival of motor neurons (SMN) complex mediates the assembly of snRNPs involved in splicing and histone RNA processing. A crucial step in this process is the binding of Sm proteins onto the SMN protein. LSm10 and LSm11, mammalian homologs of the yeast Sm proteins D1 and D2, are important for U7 snRNP function and subcellular localization. U7 snRNP is an RNA molecule involved in the splicing of animal histone pre-mRNAs. Lsm10 and Lsm11 also associate with pICln (Chloride ion current inducer protein), which interacts with Sm proteins to inhibit their assembly on U RNA. LSm10 interactions with U7 snRNA and pICln may provide the means for using modified U7 snRNA derivatives to alter specific pre-mRNA splicing events, potentially leading to advances in antisense gene therapy.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human LSM10
Purification method:
Antigen affinity purification
Target Synonym:
LSM 10;LSM10 U7 small nuclear RNA associated;MGC15749;MST074;MSTP074;U7 snRNA associated Sm like protein LSm10;U7 snRNP specific Sm like protein LSM10
UNIProt ID:
Q969L4

Documents