Elabscience

Recombinant Mouse Interleukin-2/IL-2 Protein (Active)

Product Code:
 
PKSM041320
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Application:
 
Cell Culture
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSM041320-10ug10ug£146.00
Quantity:
PKSM041320-50ug50ug£330.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
Interleukin-2;IL-2
Accession:
P04351
Activity:
Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The specific activity of Recombinant Mouse IL-2 is >1x107 IU/mg.
Background:
Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL-2 shares 56% and 73% aa sequence identity with human and rat IL-2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL-2 may be a key cytokine in the natural suppression of autoimmunity.
Calculated MW:
17.4 kDa
Endotoxin:
< 0.01 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM Sodium Citrate, 0.2%Tween 80,pH3.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
17 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala21-Gln169
Target Synonym:
IL2;Aldesleukin;Interleukin 2;Interleukin-2;IL-2;IL2;T-cell growth facter;T cell growth factor;TCGF
UNIProt ID:
P04351

Documents