Elabscience

Recombinant Human Alpha-Synuclein/SNCA Protein (Active)

Product Code:
 
PKSH033771
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSH033771-10ug10ug£106.00
Quantity:
PKSH033771-50ug50ug£166.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
SNCA
Accession:
P37840
Activity:
Recombinant Human alpha -Synuclein is ideal for use as a control substrate for in vitro Ubiquitin conjugation using select Ubiquitin E3 ligases such as CHIP/Stub1. Aggregation T1/2 time of 70 uM human alpha -Synuclein protein is 1.07h(0.5 mM SDS).
Background:
Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1; Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition; SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).
Calculated MW:
14.46 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS;PH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
17 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met1-Ala140
Target Synonym:
Alpha-Synuclein;Non-A Beta Component of AD Amyloid;Non-A4 Component of Amyloid Precursor;NACP;SNCA;NACP;PARK1
UNIProt ID:
P37840

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